Effect of a single administration of benzene, toluene or m-xylene on carboxyhaemoglobin elevation and metabolism of dichloromethane in rats. S.K. Kim and Y.C. Kim. J. Appl. Toxicology, September/October 1996, 16(5), 437--444.
The study reported was undertaken to determine the effects of a single treatment of aromatic hydrocarbons (AHCs) on the carbon monoxide generation from dichloromethane (DCM), and also to characterize the enzyme system responsible for this metabolic conversion. Since both DCM and AHCs are widely used volatile solvents, a combined exposure of workers to these chemicals may be a frequent occurrence in workplaces. 38 refs.