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UPDATED 1 Sept: The EI library in London is temporarily closed to the public, as a precautionary measure in light of the ongoing COVID-19 situation. The Knowledge Service will still be answering email queries via email , or via live chats during working hours (09:15-17:00 GMT). Our e-library is always open for members here: eLibrary , for full-text access to over 200 e-books and millions of articles. Thank you for your patience.
Role of ethanol exposure on cocaine metabolism in rat hepatocytes. M.L. Figliomeni and M.S. Abdel-Rahman. J. Appl. Toxicology, March/April 1997, 17(2), 105--112.
In the investigation reported the effect of acute ethanol exposure on cocaine metabolism was studied. An HPLC method was utilized to quantify cocaine, benzoylecognine, norcocaine and ethylcocaine formation in hepatocytes isolated from male Sprague-Dawley rats. It is shown that cocaine is taken up by cell and is biotransformed as demonstrated, by the detection of the microsomal by-products of metabolism in cellur aliquots. 46 refs.
Abstract details
Journal title: Journal of Applied Toxicology
Subjects: Natural and physical sciences, Organic Chemistry, Health and safety, Health, Safety, Toxicology
